Schizophrenia & immune activation


Researchers at the Swedish medical university Karolinska Institutet have discovered that patients with recent-onset schizophrenia have higher levels of inflammatory substances in their brains. [...]

Scientists at Karolinska Institutet have now been able to analyse inflammatory substances in the spinal fluid of patients with schizophrenia, instead of, as in previous studies, in the blood. The results show that patients with recent-onset schizophrenia have raised levels of a signal substance called interleukin-1beta, which can be released in the presence of inflammation. In the healthy control patients, this substance was barely measurable. [...]

“We would have made terrific progress if we were one day able to treat schizophrenia patients with immunotherapy, as it might then be possible to interrupt the course of the disease at an early stage of its development,” says Professor Engberg. (via.)


2 thoughts on “Schizophrenia & immune activation

  1. I’m always skeptical of the lets-find-a-molecule attitude towards therapeutic approaches. Easy to market, but usually (and I’m speaking too broadly here…) not without some serious down sides.

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