BDNF, hyperlexia, hypergraphia, seizures…


Just some loosely connected neuro-things I wanted to save somewhere.

  • Notably without citation, Wikipedia claims BDNF is also expressed in the retina, the central nervous system, motor neurons, the kidneys, and the prostate (aside from just the hippocampus and cerebral cortex). (via.)
  • BDNF knockingout in mice affects coordination, balance, hearing, taste, and breathing. “Knockout mice also exhibit cerebellar abnormalities and an increase in the number of sympathetic neurons.” (via.)
  • BDNF is increased by prolonged seizures, and important to GABA pathways. (via.)
  • Hypergraphia, a condition which afflicts individuals with a compulsive desire to write, is associated with temporal lobe epilepsy… and quite a few interesting characters have had it. (via.)
  • Hyperlexia, the extreme variety of a compulsion to read, may be caused by a “cerebral infarction in the left anterior cingulate cortex and corpus callosum.” (via.)
  • Temporal lobe epileptics are often hyposexual. (via.)